Phineas Gage

Phineas Gage and the tamping iron Public domain

In 1848, Phineas Gage experienced a catastrophic brain injury and survived -- though altered -- for more than 11 years. Over time, he morphed into one of the world's most famous case studies in how damage to the brain can affect behavior.

Topics in this Podcast: biographies, American history, disability, 19th century, medical history, U.S. history